Most Advanced Total Anti-Aging Medical Center
Eri Clinic Omotesando

Super advanced stem cells / Advanced treatment
Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”) Therapy

Eri Clinic Omotesando provides “Stem Cell Therapy” by using Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”) Therapy through the most advanced cell processing technology in Japan, which can be said to “Ultimate anti-aging therapy” for the purpose of the constitution improvement and the rejuvenation of the whole body.
A human body is composed of approximately 60 trillion cells, whose bases are stem cells, which are undifferentiated biological cells that can differentiate into specialized cells and can divide to produce more stem cells.
There have been difficulties where stem cell therapy has been provided sanitarily and safely with managing quality, although the regenerative medicines by stem cell therapy applied to cosmetic medical care recently.
Dr. Eri has decided to be strategically allied with the laboratory which has the highest cell processing technology with safety in Japan, which will provide Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”), to be used for patients safely for the purpose of the total anti-aging.

Stem Cell:
A human body is composed of approximately 60 trillion cells, whose bases are stem cells.
Stem Cells can differentiate into specialized cells and can divide to produce more stem cells.

”Regenerative Medicine / Stem Cell Therapy” Menu

Super Premium Stem Cell Therapy

Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”) Therapy

Eri Clinic Group provides Stem Cell Therapy according to the purpose of the patient by usage of Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”) Therapy by strategic alliance with the most reliable laboratory in Japan safely and efficiently.

Dental Pulp Cell is the nerve of the tooth which is in the core of the tooth, which is guarded by the stiff layer of the tooth, causing the gene not to be scared, and the cell which cannot be the cancer cell easily, therefore, include the healthy and a lot of high quality stem cells.
Dental Pulp Stem Cell has an advantage compared with well known Bone marrow-derived Stem Cell and Adipose-derived Stem Cell, because it can be safely and easily collected, isolated, and cultivated with donor`s low risk.
Additionally, because the stem cells tend to decrease rapidly with aging, the most appropriate dental pulp stem cells will be collected from baby teeth or wisdom teeth below 20 year old.
Eri Clinic is using only Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”) which includes more than 100 kinds of growth factors, cultivated from the milk teeth, having very high cell proliferation potency under the severe donor screening.

The main kinds and effects of the Growth Factor (the Cytokine) contained in Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”)

The kind of the Cytokine The main effect
Vascular Endothelial Growth Factor : VEGF The hair growth, the hair restoration
Epidermal Growth Factor : EGF and their Family Improvement of pigmentation, dullness of the skin, the scarfskin turnover, and Prevention of the wrinkles
TheLeratunocyte Growth Factor : KGF The hair growth, the hair restoration
Insulin-like Growth Factor : IGF Skin reconstruction, implovement of the wrinkles, the reconstruction of the elasticity of skin and so on, and Hair restoration
Platelet-Derived Growth Factor : PDGF The promotion of the cell division, the multiple – reconstruction of the damage organization
Transforming Growth Factor : TGF-β、TGF-α and their family Antiinflammation, the healing of wound
Hepaticyte Growth Factor : HGF The Anagenesis
Neutral Nutritional Factor CNTF (The ciliary body neurotrophic factor) Growth stimulation and acticvation of the trunk cell
GDNF (The glia cell stock origin neurotrophic factor) Differentitation and growth of the nerve cell, capture and promition of dopamine
NGF (The nerve growth factor) The synthesis – the promotion of the acetylcholine, the maintenance of the nerve cell, the restoration when damaging a cell, it prompt aging in the restoration in the cranial nerve and preventing Alzheimer disease – dementia
BDNF (The cerebral origin neurotrophic factor) The prevention of the survival maintenance – the growth promotion, Alzheimer disease – the dementia of the nerve cell
Others  

Treatment Method

[Offered] Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”) Therapy
Medication Method: Meso Therapy, Iontophoresis, Drip Infusion, Nasal Drip

Medication Method Medication Method Quantity
■ Meso Therapy
Through direct injection into the skin and the scalp, etc., the active ingredient will be sent subcutaneously, which will cause a quick effect.
1Vial
■ Iontophoresis
By passing a subtle electric current, the active ingredient will be delivered to the depth of the skin.
1Vial
■ Drip Infusion
The active ingredient, injected into the direct vein, will act on the interior of the body directly.
1Vial
2Vial
3Vial
■ Nasal Drop (Home Care)
Stem Cell Culture Supernatant (Exosome), undiluted, will be used for home care through nasal drop.
1Vial
■ Eye drops (Home care) 1Vial
■ Undiluted solution 1Vial

[Owned] Milk Teeth Dental Pulp Stem Cell Supernatant (“Exosome”) Therapy
Medication Method: Meso Therapy, Iontophoresis, Drip Infusion, Nasal Drip

Quantity of Vials
1mlx30(30sessions)
1mlx60(60sessions)
1mlx90(90sessions)

Q&A

Q1.The reason why the dental-pulp stem cells to be selected among several stem cells?

Among mesenchymal stem cells, there are dental-pulp stem cells, bone marrow-derived stem cells, cord blood-derived stem cells, placenta-derived stem cells, and adipose-derived stem cells. Bone marrow-derived stem cells and Cord blood-derived stem cells will be effective for blood formation, then only to be useful for Leukemia and Anaplastic anemia, while Placenta-derived stem cells are unclear to be extracted, and unstable for safety.Regarding Adipose-derived stem cells, most of the fat origin stem cells have been taken through liposuction, where mostly likely with diseases such as diabetes and arteriosclerosis, then the high effect will NOT be stable.On the other hands, regarding dental-pulp stem cells, it is most easier to extract from the baby teeth and wisdom teeth, which has a high growth factor with high quality and safety.

Kinds of MCSs (Mesenchymal Stem Cells)Pros and Cons
Dental Pulp-derived MSCs ◎It is the most easiest and the most stable to extract from the milk teeth and wisdom teeth, which has a high growth factor.
Bone Marrow-derived MSCsIt is very difficult and with serious pain to extract, and it is only effective for blood formation, then only to be useful for Leukemia and Aplastic anemia.
Cord Blood-derived MSCsIt is very unclear how to extract, and it is only effective for blood formation, then only to be useful for Leukemia and Aplastic anemia.
Placenta-derived MSCsIt is very unclear how to extract, and it could be unstable for safety.
Adipose-derived MSCsMost of the fat origin stem cells have been taken through liposuction, where mostly likely with diseases such as diabetes and arteriosclerosis, then the high effect will NOT be stable.
* In our “Adipose-derived stem cell therapy”, we carry out treatment by extracting stem cells from your own fat, culturing then sending the cultured cells back to your body.

Q2.Different from PRP (Platelet-Rich Plasma)?

PRP is without “Culture”, then different from stem cell therapy, with much less the growth factor and cytokine, therefore, this method cannot be “Regenerative Medicine” It is reported that skin troubles such as inflammation has been caused by PRP.

“Super Premium Stem Cell Therapy”
Most Advanced Regenerative Medicine Example

Meso Therapy to the skin
(Endodermic-injection to the face)

Female in her 50s 1 time
Female in her 50s 1 time
Improvement of Wrinkle and Pores
Female in her 50s 1 time
Female in her 50s 1 time
Improvement of skin texture and beautiful skin rejuvenation effectively

Meso Therapy to the hair scalp
(Endodermic-injection)

Male in his 50s (w/ Drip Infusion) 4 times
Male in his 50s (w/ Drip Infusion) 4 times
Male in his 50s (w/ Drip Infusion) 4 times
Improvement Hair Restoration to be proven
Female in her 50s 5 times
Female in her 50s 5 times
Improvement Hair Restoration as well as Hair Grayness

Besides, the effect can look forward to a various allergic-disease, an atopic dermatitis, cervical vertebra lumbago, a demented disease, Parkingson’s disease prevention, diet, a stiff shoulder, an athlete (Muscular strength, Immune strength) and so on, too.



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